Scholar Profile

Bo Huang

Assistant Professor
Department of Pharmaceutical Chemistry
University of California, San Francisco
UCSF Mission Bay Campus
1700 4th St., MC 2532
San Francisco, CA 94158
Voice: 415-476-1866
Fax: 415-502-8298
Personal Homepage
2010 Searle Scholar

Research Interests

Cellular processes are often carried out by coordinated participation of many proteins. To understand how them work together, we are developing super-resolution microscopy and single-molecule imaging methods and using them to study the following problems:

(1) proteins organization in large complexes such as the nuclear pore complex and centrosome,

(2) dynamic protein interaction in regulating G-protein coupled receptor signaling,

(3) cell adhesion molecules in controlling the development of the nervous system, and,

(4) protein-DNA interactions in the nucleus.

We are also interested in combining synthetic chemistry, protein engineering and microfluidics-based high-throughput screening to create new fluorescent probes that allow us to better study these cellular structures and processes.