Scholar Profile

Alexandra C. Newton

Department of Pharmacology
University of California, San Diego
9500 Gilman Drive
La Jolla, CA 92093-0640
Voice: 858-534-4527
Fax: 858-534-6020
Personal Homepage
1989 Searle Scholar

Research Interests

Our lab investigates the biology and chemistry of protein kinase C and its upstream kinase, the phosphoinositide-dependent kinase, PDK-1. We are interested in the coordinated regulation of both these enzymes in cellular signalling. Current projects focus on the molecular mechanisms governing the regulation of these key signalling kinases by:

  • lipid interactions
  • regulatory and targeting proteins
  • phosphorylation