Conducting research on biomodels and laboratory animals

The execution of biomedical research of pharmacological drugs, testing of medical instruments, devices and devices, new invasive (surgical) methods of treatment of patients requires obligatory preliminary determination of their safety for humans by organizing preclinical tests and testing.

 

Most often the preclinical testing is carried out in experiments on laboratory animals. At the same time, some types of preclinical studies, particularly when developing and justifying new methods of surgical interventions (for example, have to be modeled and performed on human cadavers, organ complexes and individual organs (anatomical specimens). These types of biomedical research are aimed primarily at expanding the scientific database on the norm and pathology of human development, as well as assessing the safety, effectiveness or usefulness of a medical product, procedure or effect. It is also necessary to take into account the educational objectives of medical universities and special secondary educational institutions (medical schools), where the curricula and programs provide for mandatory training practices aimed at mastering the practical skills, invasive medical procedures, emergency surgical operations required in providing care, especially in extreme situations.

 

Mastering of these techniques can be provided only by organizing systematic work of students and pupils on human cadavers, as well as performing training and experimental operations on large laboratory animals. Unfortunately, at present, these tasks of the educational process have no alternative solution. Moreover, from the point of view of implementation of the main task of educational institution of medical profile – preparation of qualified specialists possessing basic manual skills, invasive manipulations and surgical techniques for providing emergency medical care – performance of practical work on cadavers of people and laboratory animals by students should be considered as a way of testing of student’s preparedness for independent practical work in clinical conditions.

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